Prophylactic effects of Kaempferia Galanga against Plasmodium berghei: in vivo study
نویسندگان
چکیده
Recently, medicinal plants have been the main source in treating malaria. Kaempferia galanga was investigated as an antioxidant, and anti-inflammation. In vivo study of K. had verified antimalarial for severe The objective this is to investigate chemoprophylactic effect, body composition, blood parameters against Plasmodium berghei. prophylactic effects were determined by employing (50; 100 200 mg/kg) mice infected with P. Mice subdivided into 4 groups (control negative 3 treatment groups). received daily days before inoculation Each inoculated containing 106 Parasitemia weight calculated every day until 5 post-inoculation, monitored 5. parasitemia on fifth after revealed a significant suppresses effect compared control (p<0.05). suppressed doses 50 mg/kg; mg/kg 0.83%; 1.96%; 2.82%, 17.8% respectively. normal, but group decreased normal group. possess
منابع مشابه
in vivo antimalarial effects of iranian flora artemisia khorassanica against plasmodium berghei and pharmacochemistry of its natural components
background : the aim of this study was to evaluate the antimalarial effects of iranian flora artemisia khorassanica against plasmodium berghei in vivo and pharmacochemistry of its natural components. methods : the aerial parts of iranian flora a. khorasanica were collected at flowering stage from khorassan province, northeastern iran in 2008. they were air-dried at room temperature; powder was ...
متن کاملThe Curative and Prophylactic Effects of Xylopic Acid on Plasmodium berghei Infection in Mice
Efforts have been intensified to search for more effective antimalarial agents because of the observed failure of some artemisinin-based combination therapy (ACT) treatments of malaria in Ghana. Xylopic acid, a pure compound isolated from the fruits of the Xylopia aethiopica, was investigated to establish its attributable prophylactic, curative antimalarial, and antipyretic properties. The anti...
متن کاملEvaluation of the antimalarial effect of Ferulago angulata (Schlecht.) Boiss. extract and suberosin epoxide against Plasmodium berghei in comparison with chloroquine using in vivo test
Background: Resistance to most antimalarial drugs has encouraged the development of novel drugs. An alternative source for discovering such drugs is natural products. Some Ferulago species are used in folk medicine for their sedative, tonic and anti-parasitic effects. Besides, coumarins isolated from this genus found to have in vitro anti-leishmanicidal effect. The present study is aimed to eva...
متن کاملEvaluation of the antimalarial effect of Ferulago angulata (Schlecht.) Boiss. extract and suberosin epoxide against Plasmodium berghei in comparison with chloroquine using in vivo test
Background: Resistance to most antimalarial drugs has encouraged the development of novel drugs. An alternative source for discovering such drugs is natural products. Some Ferulago species are used in folk medicine for their sedative, tonic and anti-parasitic effects. Besides, coumarins isolated from this genus found to have in vitro anti-leishmanicidal effect. The present study is aimed to eva...
متن کاملAntimalarial efficacy of Albizia lebbeck (Leguminosae) against Plasmodium falciparum in vitro & P. berghei in vivo.
BACKGROUND & OBJECTIVES Albizia lebbeck Benth. (Leguminosae) has long been used in Indian traditional medicine. The current study was designed to test antimalarial activity of ethanolic bark extract of A. lebbeck (EBEAL). METHODS EBEAL was prepared by soxhlet extraction and subjected to phytochemical analysis. The extract was evaluated for its in vitro antimalarial activity against Plasmodium...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Jurnal Teknologi Laboratorium
سال: 2022
ISSN: ['2338-5634', '2580-0191']
DOI: https://doi.org/10.29238/teknolabjournal.v10i2.283